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1

Cytostatic/Cytotoxic Effects of 5-Fluorouridine Nucleolipids on Colon, Hepatocellular, and Renal Carcinoma Cells: in vitro Identification of a Potential Cytotoxic Multi-Anticancer Drug

Farhat, Anisa, Malecki, Edith, Bonaterra, Gabriel A., Röthlein, Doris, Wolf, Martin, Schmitt, Jürgen, Rosemeyer, Helmut, Kinscherf, Ralf

Journal:

Chemistry & Biodiversity

Year:

2014

Language:

english

File:

PDF, 654 KB

english, 2014

2

Ein Nucleolipid mit dem antiviralen Acycloguanosin als Kopfgruppe - Synthese und Liposomenbildung

Dr. Helmut Rosemeyer, Michael Ahlers, Brigitta Schmidt, Prof. Dr. Frank Seela

Journal:

Angewandte Chemie

Year:

1985

Language:

german

File:

PDF, 346 KB

german, 1985

3

Specific DNA Duplex Formation at an Artificial Lipid Bilayer: towards a New DNA Biosensor Technology

Emma Werz, Sergei Korneev, Malayko Montilla-Martinez, Richard Wagner, Roland Hemmler, Claudius Walter, Jörg Eisfeld, Karsten Gall, Helmut Rosemeyer

Journal:

Chemistry & Biodiversity

Year:

2012

Language:

english

File:

PDF, 4.01 MB

english, 2012

4

Nucleoterpenes of Thymidine and 2′-Deoxyinosine: Synthons for a Biomimetic Lipophilization of Oligonucleotides

Köstler, Karl, Werz, Emma, Malecki, Edith, Montilla-Martinez, Malayko, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2013

Language:

english

File:

PDF, 4.35 MB

english, 2013

5

Nucleolipids of the Cancerostatic 5-Fluorouridine: Synthesis, Adherence to Oligonucleotides, and Incorporation in Artificial Lipid Bilayers

Malecki, Edith, Ottenhaus, Vanessa, Werz, Emma, Knies, Christine, Montilla Martinez, Malayko, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

6

Cyclohexene Nucleic Acids (CeNA): Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA

Wang, Jing, Verbeure, Birgit, Luyten, Ingrid, Lescrinier, Eveline, Froeyen, Matthias, Hendrix, Chris, Rosemeyer, Helmut, Seela, Frank, Van Aerschot, Arthur, Herdewijn, Piet

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 175 KB

english, 2000

7

‘Yeast Mail’: A Novel Saccharomyces Application (NSA) to Encrypt Messages

Rosemeyer, Helmut, Paululat, Achim, Heinisch, Jürgen J.

Journal:

Chemistry & Biodiversity

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

8

Immobilization of 5-Fluorouridine on Chitosan

Malecki, Edith, Viere, Rebecca, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2013

Language:

english

File:

PDF, 1.09 MB

english, 2013

9

Synthesis of 5-Fluorouridine Nucleolipid Derivatives and Their Cytostatic/Cytotoxic Activities on Human HT-29 Colon Carcinoma Cells

Malecki, Edith, Farhat, Anisa, Bonaterra, Gabriel A., Röthlein, Doris, Wolf, Martin, Schmitt, Jürgen, Kinscherf, Ralf, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2013

Language:

english

File:

PDF, 633 KB

english, 2013

10

Extraordinary Thermal Stability of an Oligodeoxynucleotide Octamer Constructed from Alternating 7-Deaza-7-iodo guanine and 5-Iodocytosine Base Pairs - DNA Duplex Stabilization by Halogen Bonds?

Ramzaeva, Natalya, Eickmeier, Henning, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

11

Mitsunobu Reactions of 5-Fluorouridine with the Terpenols Phytol and Nerol : DNA Building Blocks for a Biomimetic Lipophilization of Nucleic Acids

Malecki, Edith, Knies, Christine, Werz, Emma, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2013

Language:

english

File:

PDF, 753 KB

english, 2013

12

Mitsunobu Alkylation of Cancerostatic 5-Fluorouridine with (2 E )-10-Hydroxydec-2-enoic Acid, a Fatty Acid from Royal Jelly with Multiple Biological Activities

Ottenhaus, Vanessa, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2015

Language:

english

File:

PDF, 462 KB

english, 2015

13

Ameliorated or Acquired Cytostatic/Cytotoxic Properties of Nucleosides by Lipophilization

Knies, Christine, Bonaterra, Gabriel, Hammerbacher, Katharina, Cordes, Andrea, Kinscherf, Ralf, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2015

Language:

english

File:

PDF, 8.94 MB

english, 2015

14

Novel Nucleolipids of Pyrimidine β - D -Ribonucleosides: Combinatorial Synthesis, Spectroscopic Characterization, and Cytostatic/Cytotoxic Activities

Knies, Christine, Hammerbacher, Katharina, Bonaterra, Gabriel A., Kinscherf, Ralf, Rosemeyer, Helmut

Journal:

Chemistry & Biodiversity

Year:

2016

Language:

english

File:

PDF, 7.67 MB

english, 2016

15

Synthesis and Pairing Properties of Oligonucleotides Containing 3-Hydroxy-4-hydroxymethyl-1-cyclohexanyl Nucleosides

Yuris Maurinsh, Helmut Rosemeyer, Robert Esnouf, Andrei Medvedovici, Jing Wang, Griet Ceulemans, Eveline Lescrinier, Chris Hendrix, Roger Busson, Pat Sandra, Frank Seela, Arthur Van Aerschot, Piet Her

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 262 KB

english, 1999

16

D-Altritol Nucleic Acids (ANA): Hybridisation Properties, Stability, and Initial Structural Analysis

Brigitte Allart, Kamran Khan, Helmut Rosemeyer, Guy Schepers, Chris Hendrix, Klaus Rothenbacher, Frank Seela, Arthur Van Aerschot, P. Herdewijn

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 145 KB

english, 1999

17

2-Aza-2′-deoxyadenosine: Synthesis, Base-Pairing Selectivity, and Stacking Properties of Oligonucleotides

Tamizi Sugiyama, Enno Schweinberger, Zygmunt Kazimierczuk, Natalya Ramzaeva, Helmut Rosemeyer, Frank Seela

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 181 KB

english, 2000

18

The High-Anti Conformation of 7-Halogenated 8-Aza-7-deaza-2′-deoxy-guanosines: A Study of the Influence of Modified Bases on the Sugar Structure of Nucleosides

Frank Seela, Georg Becher, Helmut Rosemeyer, Hans Reuter, Guido Kastner, Igor A. Mikhailopulo

Journal:

Helvetica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

19

7-Desaza-2′-desoxyxanthosin-Dihydrat bildet H2O-haltige Nanoröhren mit C-H⋅⋅⋅O-Wasserstoffbrücken

Frank Seela, Thomas Wiglenda, Helmut Rosemeyer, Henning Eickmeier, Hans Reuter

Journal:

Angewandte Chemie

Year:

2002

Language:

german

File:

PDF, 116 KB

german, 2002

20

α-Homo-DNA and RNA Form a Parallel Oriented Non-A, Non-B-Type Double Helical Structure

Matheus Froeyen, Eveline Lescrinier, Luc Kerremans, Helmut Rosemeyer, Frank Seela, Birgit Verbeure, Irene Lagoja, Jef Rozenski, Arthur Van Aerschot, Roger Busson, Piet Herdewijn

Journal:

Chemistry - A European Journal

Year:

2001

Language:

english

File:

PDF, 260 KB

english, 2001

21

7-Deaza-2′-deoxyxanthosine Dihydrate Forms Water-Filled Nanotubes with C−H⋅⋅⋅O Hydrogen Bonds

Frank Seela, Thomas Wiglenda, Helmut Rosemeyer, Henning Eickmeier, Hans Reuter

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 226 KB

english, 2002

22

Oligonucleotides Functionalized by Fluorescein and Rhodamine Dyes: Michael Addition of Methyl Acrylate to 2′-Deoxypseudouridine

Natalya Ramzaeva, Helmut Rosemeyer, Peter Leonard, Klaus Mühlegger, Frank Bergmann, Herbert von der Eltz, Frank Seela

Journal:

Helvetica Chimica Acta

Year:

2000

Language:

english

File:

PDF, 350 KB

english, 2000

23

5-Aza-7-deazaguanine DNA: Recognition and Strand Orientation of Oligonucleotides Incorporating Anomeric Imidazo[1,2-a]-1,3,5-triazine Nucleosides

Frank Seela, Stefan Amberg, Alexander Melenewski, Helmut Rosemeyer

Journal:

Helvetica Chimica Acta

Year:

2001

Language:

english

File:

PDF, 182 KB

english, 2001

24

Selection of New Sequence-Selective Unnatural Peptides Binding to Double-Stranded Deoxyribonucleic Acids (dsDNA) by Means of a Gel-Retardation Experiment for Library Analysis

Patrick Chaltin, Eveline Lescrinier, Theo Lescrinier, Jef Rozenski, Chris Hendrix, Helmut Rosemeyer, Roger Busson, Arthur Van Aerschot, Piet Herdewijn

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 321 KB

english, 2002

25

Dextranverknüpftes N6-(2-Isopentenyl)adenosin -ein polymergebundener Antimetabolit mit „Sollbruchstelle”

Dr. Helmut Rosemeyer, Prof. Dr. Frank Seela

Journal:

Angewandte Chemie

Year:

1984

Language:

german

File:

PDF, 310 KB

german, 1984

26

Dextran-Linked N6-(2-Isopentenyl)adenosine—A Polymer-Bound Antimetabolite with a Predetermined Cleavage Position

Dr. Helmut Rosemeyer, Prof. Dr. Frank Seela

Journal:

Angewandte Chemie International Edition

Year:

1984

Language:

english

File:

PDF, 286 KB

english, 1984

27

A Nucleolipid with Antiviral Acycloguanosine as Head Group—Synthesis and Liposome Formation

Dr. Helmut Rosemeyer, Dipl.-Chem. Michael Ahlers, Dipl.-Chem. Brigitta Schmidt, Prof. Dr. Frank Seela

Journal:

Angewandte Chemie International Edition

Year:

1985

Language:

english

File:

PDF, 245 KB

english, 1985

28

The Chemodiversity of Purine as a Constituent of Natural Products

Helmut Rosemeyer

Journal:

Chemistry & Biodiversity

Year:

2004

Language:

english

File:

PDF, 1.05 MB

english, 2004

29

Nucleolipids: Natural Occurrence, Synthesis, Molecular Recognition, and Supramolecular Assemblies as Potential Precursors of Life and Bioorganic Materials

Helmut Rosemeyer

Journal:

Chemistry & Biodiversity

Year:

2005

Language:

english

File:

PDF, 1.63 MB

english, 2005

30

Conformational and Chiral Selection of Oligonucleotides

Matheus Froeyen, François Morvan, Jean-Jacques Vasseur, Peter Nielsen, Arthur Van Aerschot, Helmut Rosemeyer, Piet Herdewijn

Journal:

Chemistry & Biodiversity

Year:

2007

Language:

english

File:

PDF, 846 KB

english, 2007

31

Hoogsteen vs. Watson–Crick Base Pairing: Incorporation of 2-Substituted Adenine- and 7-Deazaadenine 2′-Deoxy-β-D-ribonucleosides into Oligonucleotides

Natalya Ramzaeva, Elisabeth Michalek, Zygmunt Kazimierczuk, Frank Seela, Helmut Rosemeyer

Journal:

Chemistry & Biodiversity

Year:

2007

Language:

english

File:

PDF, 300 KB

english, 2007

32

1′, 5′ -Anhydrohexitol Oligonucleotides: Synthesis, Base Pairing and Recognition by Regular Oligodeoxyribonucleotides and Oligoribonucleotides

Dr. Chris Hendrix, Dr. Helmut Rosemeyer, Dr. Ilse Verheggen, Dr. Arthur Van Aerschot, Prof. Dr. Frank Seela, Prof. Dr. Piet Herdewijn

Journal:

Chemistry - A European Journal

Year:

1997

Language:

english

File:

PDF, 1.22 MB

english, 1997

33

1′,5′-Anhydrohexitol Oligonucleotides: Hybridisation and Strand Displacement with Oligoribonucleotides, Interaction with RNase H and HIV Reverse Transcriptase

Dr. Chris Hendrix, Dr. Helmut Rosemeyer, Dr. Bart De Bouvere, Dr. Arthur Van Aerschot, Prof. Dr. Frank Seela, Prof. Dr. Piet Herdewijn

Journal:

Chemistry - A European Journal

Year:

1997

Language:

english

File:

PDF, 1.26 MB

english, 1997

34

Solution Structure and Conformational Dynamics of Deoxyxylonucleic Acids (dXNA): An Orthogonal Nucleic Acid Candidate

Mohitosh Maiti, Vanessa Siegmund, Dr. Mikhail Abramov, Prof. Dr. Eveline Lescrinier, Prof. Dr. Helmut Rosemeyer, Dr. Mathy Froeyen, Prof. Dr. Amutha Ramaswamy, Prof. Dr. Arnout Ceulemans, Prof. Dr. An

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 1.73 MB

english, 2012

35

ChemInform Abstract: Oligonucleotides Functionalized by Fluorescein and Rhodamine Dyes: Michael Addition of Methyl Acrylate to 2′-Deoxypseudouridine.

Natalya Ramzaeva, Helmut Rosemeyer, Peter Leonard, Klaus Muehlegger, Frank Bergmann, Herbert von der Eltz, Frank Seela

Journal:

Year:

2000

File:

PDF, 25 KB

2000

36

ChemInform Abstract: 5-Aza-7-deazaguanine DNA: Recognition and Strand Orientation of Oligonucleotides Incorporating Anomeric Imidazo[1,2-a]-1,3,5-triazine Nucleosides.

Frank Seela, Stefan Amberg, Alexander Melenewski, Helmut Rosemeyer

Journal:

Year:

2001

File:

PDF, 25 KB

2001

37

ChemInform Abstract: Pyrophosphoryl Derivatives of 1-(2-Deoxy-3-O-phosphonomethyl-β- and -α-D-erythro-pentofuranosyl)thymine: Synthesis and Substrate Properties Towards Some DNA Polymerases.

Igor A. Mikhailopulo, Tamara I. Kulak, Olga V. Tkachenko, Svetlana L. Sentyureva, Lyubov S. Victorova, Helmut Rosemeyer, Frank Seela

Journal:

Year:

2002

Language:

english

File:

PDF, 35 KB

english, 2002

38

ChemInform Abstract: The α-D Anomer of 5-Aza-7-deaza-2′-deoxyguanosine.

Frank Seela, Helmut Rosemeyer, Alexander Melenewski, Eva-Maria Heithoff, Henning Eickmeier, Hans Reuter

Journal:

Year:

2002

File:

PDF, 28 KB

2002

39

ChemInform Abstract: Selection of New Sequence-Selective Unnatural Peptides Binding to Double-Stranded Deoxyribonucleic Acids (dsDNA) by Means of a Gel-Retardation Experiment for Library Analysis.

Patrick Chaltin, Eveline Lescrinier, Theo Lescrinier, Jef Rozenski, Chris Hendrix, Helmut Rosemeyer, Roger Busson, Arthur Van Aerschot, Piet Herdewijn

Journal:

Year:

2002

File:

PDF, 27 KB

2002

40

5-Aza-7-deazapurines: Synthesis and Properties of Nucleosides and Oligonucleotides

Frank Seela, Helmut Rosemeyer

Journal:

Year:

2003

File:

PDF, 51 KB

2003

41

The Chemodiversity of Purine as a Constituent of Natural Products

Helmut Rosemeyer

Journal:

Year:

2004

File:

PDF, 17 KB

2004

42

Spontane Öffnung des Pyrimidinringes in Pyrrolo[2,3-d]pyrimidinen nach intramolekularer Acylierung

Helmut Rosemeyer, Klaus Kaiser, Frank Seela, Volker Zabel, Wolfram Saenger

Journal:

Helvetica Chimica Acta

Year:

1985

File:

PDF, 674 KB

1985

43

Cyclisation of 7-Deazaxanthine-9-propionic Acid to an Active-Site-Directed, Irreversibly Acting Inhibitor of Xanthine Oxidase

Helmut Rosemeyer, Uwe Kretschmer, Frank Seela

Journal:

Helvetica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 470 KB

english, 1985

44

Stereoselective synthesis of pyrrolo[2,3-d]pyrimidine α- and β-D-ribonucleosides from anomerically pure D-ribofuranosyl chlorides: Solid-Liquid Phase-Transfer Glycosylation and 15N-NMR Spectra

Helmut Rosemeyer, Frank Seela

Journal:

Helvetica Chimica Acta

Year:

1988

Language:

english

File:

PDF, 710 KB

english, 1988

45

2′, 3′-Dideoxy-3′-fluorotubercidin and Related Dideoxyribonucleosides:. Synthesis via a 2′-deoxy-3′-oxoribofuranoside intermediate and conformation studies

Helmut Rosemeyer, Frank Seela

Journal:

Helvetica Chimica Acta

Year:

1989

Language:

english

File:

PDF, 716 KB

english, 1989

46

Synthesis of 3-Deaza-2′-deoxyadenosine and 3-Deaza-2′,3′-dideoxyadenosine: Glycosylation of the 4-Chloroimidazo[4,5-c]pyridinyl Anion

Frank Seela, Helmut Rosemeyer, Sabine Fischer

Journal:

Helvetica Chimica Acta

Year:

1990

Language:

english

File:

PDF, 589 KB

english, 1990

47

1-(2′-Deoxy-β-D-xylofuranosyl)thymine Building Blocks for Solid-Phase Synthesis and Properties of Oligo(2′-Deoxyxylonucleotides)

Helmut Rosemeyer, Frank Seela

Journal:

Helvetica Chimica Acta

Year:

1991

Language:

english

File:

PDF, 710 KB

english, 1991

48

Nucleosides. Part L.. Structure of lumazine N1-(2′-deoxy-D-ribonucleosides) ( = 1-(2′-deoxy-D-ribofuranosyl)pteridine-2,4(1H,3H)-diones): A revision of the anomeric configuration

Xiaodong Cao, Wolfgang Pfleiderer, Helmut Rosemeyer, Frank Seela, Willi Bannwarth, Peter Schönholzer

Journal:

Helvetica Chimica Acta

Year:

1992

Language:

english

File:

PDF, 369 KB

english, 1992

49

1-(2′-Deoxy-β-D-xylofuranosyl)cytosine: Base pairing of oligonucleotides with a configurationally altered sugar-phosphate backbone

Frank Seela, Karlheinz Wörner, Helmut Rosemeyer

Journal:

Helvetica Chimica Acta

Year:

1994

Language:

english

File:

PDF, 811 KB

english, 1994

50

Synthesis of 4-Substituted 1H-Benzimidazole 2′-Deoxyribonucleosides and Utility of the 4-Nitro Compound as Universal Base

Frank Seela, Werner Bourgeois, Helmut Rosemeyer, Thomas Wenzel

Journal:

Helvetica Chimica Acta

Year:

1996

Language:

english

File:

PDF, 623 KB

english, 1996